An Investigation of Certain Inflammatory Markers in Whole Blood in Patients with Feline Panleukopenia
Inflammatory Markers in Whole Blood in Panleukopenia Cats
DOI:
https://doi.org/10.5281/zenodo.23403965Keywords:
FPV, Inflammation Index, Whole Blood, NLR, SIRIAbstract
Feline Panleukopenia Virus (FPV) is a highly contagious viral infection, most commonly observed in young and unvaccinated cats, characterized by high morbidity and mortality rates. Although several diagnostic methods exist, recent studies have increasingly emphasized the use of inflammation indicators derived from complete blood count (CBC) in the diagnosis and management of FPV. In the present study, CBC results from 25 infected cats (older than 45 days, regardless of sex) presenting to a veterinary hospital with complaints of vomiting and diarrhea, along with 10 healthy cats, were evaluated. Derived hematological indices including Neutrophil-to-Lymphocyte Ratio (NLR), Lymphocyte-to-Monocyte Ratio (LMR), Platelet-to-Lymphocyte Ratio (PLR), Systemic Immune-Inflammation Index (SII), Systemic Inflammatory Response Index (SIRI), Pan-Immune Inflammation Value (PIV), and Neutrophil-Monocyte-Lymphocyte Ratio (NMLR) were analyzed. The study demonstrated statistically significant differences in NLR (p = 0.008), PLR (p = 0.019), NMLR (p = 0.007), SII (p < 0.001), SIRI (p = 0.001), and PIV (p < 0.001). These findings suggest that such parameters may serve as valuable tools in the diagnosis, clinical management, and prognostic assessment of FPV. It is concluded that with further comprehensive studies, the clinical utility of these indices will gain increasing importance.
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