Turkish Journal of Veterinary Internal Medicine

The Investigation of Adrenomedulline Levels in Dogs with Heart Failure

Buğrahan Bekir Yağcı — 2024-01-11

In this study, it was intention to investigate adrenomedulline (ADM) level in dogs with heart failure. Animal materials within the scope of the study; 20 diagnosis of heart failure have been refferal to Kırıkkale Veterinary Faculty Education and Research hospital without age, gender and racial discrimination. At the same time, blood samples were taken from 10 healthy dogs with no heart failure (control group). Serum samples were obtained from blood samples; for the examination of adrenomedulline enzyme - connected immunosorbent test kit. In the assessments; while the ADM level was looked high in dogs with heart failure, it was not registered as high in the control group.As a result of the examinations, a significant increase in the value of adrenomedulline in dogs with heart faiulre.

Intestinal Permeability Among Calves with Behavioural Disturbances

Hasan ERDOĞAN — 2024-01-11

The connection among disturbed intestinal ecosystem, namely dysbiosis, and central nervous system have been recognized and evidence of proofed within the last 10 years. Microbiological alterations consequently give rise to elevated intestinal permeability, and thus the perception of bacterial fragment and toxins. This could easily hasten and instigate local/systemic inflammatory respond, acting on distant organs, involving the brain. Moreover the unfication of intestinal epithelial barrier exhibits a pivotal role for the microbiota–gut–brain axis. Novel discovery on zonulin, a signfifcant tight junction modifyer of intestinal epithelial cells, has been recognized to participate within the blood–brain barrier functioning. In the present article the present authors’ addressed the possible role of zonulin in an attempt to detect the relationship among leaky gut, neurological involvement and gut-brain axis to those of calves. Serum zonulin levels were determined by use of Sandwich ELISA. Clinical signs were recorded and noticed. Comparative analysis of serum zonulin levels (ng/mL) were deemed available were showing statistical significance (p=0,001) among healthy ones (24,11 ± 2,44) vs. calves with behavioural disturbances (58,03 ± 2,47).

Hydronephrosis A rare anomaly: Advanced Congenital Hydronephrosis in a Cat

Başar Ulaş SAYILKAN — 2024-01-11

Hydronephrosis; is an abnormal condition that is the structures of the kidney, characterized by atrophy of the renal parenchyma and dilatation of the renal pelvis. It can occur due to congenital or acquired reasons. A 2-month-old female, mixed breed cat was admitted to our outpatient clinic with complaints of loss of appetite and vomiting for a week, which did not improve despite being treated in different clinics. The patient was applied for general physical examination, complete blood count, serum biochemistry analysis, urinalysis, and abdominal ultrasonography. In the general physical examination of the patient, it was determined that the kidneys were smaller than usual and had irregular borders. Nonregenerative, normochromic, and normocytic anemia were found in the complete blood count. In the serum biochemistry analysis, urea and creatinine values were much higher than usual. Proteinuria was found in urine analysis, and Urine Specific Gravity was determined as 1010. As a result of ultrasonographic imaging performed on our patient, it was determined that both kidneys were grade IV hydronephrotic. Nephrectomy or pyelography was not considered necessary. The owner was informed that the prognosis would be poor and euthanasia was recommended. The patient's owner refused euthanasia.

Portosystemic Shunt in Dogs and Cats: A Retrospective Clinical Review

Ali Evren Haydardedeoğlu — 2024-01-11

Portosystemic shunt (PSS) is the most common cause of hepatic encephalopathy in dogs and cats. PSS are vascular comminications taking blood directly from portal circulation to the systemic circulation bypassing the liver in process. In this clinical case study; congenital portosystemic shunt causing signs of hepatic encephalopathy were diagnosed in 2 cats and 2 dogs. Medical records between 2009–2011 years of dogs and cats with clinical, hematological, biochemistrical and ultrasonografic confirmed PSS were reviewed. Clinical anemnesis was taken hepatic encephalopathy signs. Hematological and serum biochemistry profile have been identified high level preprandial and postprandial bile acid and Ultrasonografic examination have been diagnosed portosystemic shunt.