Turkish Journal of Veterinary Internal Medicine

Zonulin Levels in Calves with Respiratory Distress Syndrome: Is There Field Evidence of Proof for Gut-Lung Axis in Calves?

2025-01-28T16:52:57+03:00

Zonulin, a highly recognized protein, influence the integrity of intercellular connections among intestinal route. Respiratory disease syndrome (rDs), has been denoted as insufficient oxygen demands along with elevated retention of carbon dioxide among neonatal calves causing respiratory acidosis. The latter syndrome has been more frequently detected among premature calves, dedicated/linked to surfactant deficiency. The present article, namely field study discussed ‘gut-lung axis’ in calves with rDs, along with searching for the evidence of leaky gut and intestinal permability alterations. Therefore, the objective of this present field study was to make interpretation for gut-lung axis in calves with rDs. In field conditions to those 5 different milk-fed veal facilities donated farms, 78 calves were were classified as healthy (n=19) or with rDs (n=59). Commercially available specific Bovine Zonulin ELISA test kits were used. The mean zonulin levels (ng/mL) in calves with rDs presenting score 2 and score 3 were detected as 66,71± 4,602 respectively denoting statistically significant alterations in contrast to healthy calves 21.69±4.234 (p<0.05). Conclusion: It should not be unwise to draw preliminary message that gut-lung axis existed in calves with rDs to those of which treatment practices should be directed to intestinal environment.

The Role of Ultrasonography in 20 Calf with Pneumonia: Diagnostic and Prognostic Value

2024-01-11T15:32:08+03:00

This study aims to show the importance of ultrasonography in assessing the severity of
pneumonia in calves and they determine the prognostic value of lung lesions.For this purpose,
20 calves that were brought to the animal hospital of Ondokuz Mayıs University with the
complaint of respiratory system complaints, included in the study. Thoracic ultrasonography
was performed by the same operator as all calves. The area between right 1-10th and left 2-
10th intercostal spaces scanned for lung lesions. The area was swabbed with %70 isopropyl
alcohol to remove the excess oil, and acoustic gel was applied. The hair was not clipped or
shaved from the chest. In calves, 2.5-6.6 MHz convex probe with 5-15 cm depth was used.
Thoracic ultrasonography was performed to both side of thorax and findings was noted as
comet-tail artifacts (COMT), diffuse comet- tail artifacts, pleural irregularities, effusions, lung
consolidations, and hepatized areas of the lung. The most common lesions were determined as
COMT (23.3%) and pleural irregularities (25.23%), and also appearance of COMT artefacts
and pleural irregularities were found higher in the right side of thorax (P>0.05). Diagnosis of
thoracic diseases were made on the basis of clinical and ultrasonographic findings and
confirmed in nine patients in necropsy. Hepatization of the lung (10.28%) and effusion
(6.54%) in the thoracal cavity was found in these calves. In conclusion ultrasonography is
useful tool for detecting lung lesions and making decision severity of lesions.

Icterus in Cats

2024-09-04T00:18:40+03:00

Icterus in cats is characterized by the yellowing of the skin, eyes, and mucous membranes due to an increase in bilirubin levels in the blood. It is a serious symptom that necessitates a thorough evaluation to determine the underlying cause. It has been reported that icterus in cats does not have any age, breed, or gender predisposition. Also known as hyperbilirubinemia, icterus can result from various conditions such as liver damage, infections, bile duct obstructions, and hemolysis. Icterus is classified into three types based on its mechanism of formation: prehepatic, hepatic, and posthepatic icterus. Clinical signs, ultrasonography, radiography, and various laboratory tests are crucial for the diagnosis of icterus. Since icterus can develop due to various factors, accurate diagnosis forms the basis of treatment, and treatment procedures are developed separately for each cause.

Management of Non-Regenerative Anaemia in Cats

2024-08-16T11:39:55+03:00

Non-regenerative anemia is a common condition in cats. Non-regenerative anemia in cats is a condition caused byinsufficient erythrocyte production or impaired erythropoiesis. Non-regenerative anemia occurs in cats of all ages , whichis characterized by a low number of erythrocytes in the blood and, as a result, a decrease in oxygen-carrying capacity. Theetiology of non-regenerative anemia in cats is a complex issue and includes a variety of conditions such as acute bloodloss, infectious diseases such as Feline leukemia virus (FeLV), Feline infectious peritonitis, and immune hemolyticanemia. It is usually associated with a variety of causes, such as iron deficiency, chronic diseases, toxin exposure, orgenetic factors. Symptoms include fatigue, pale gums, loss of appetite, and weakness. The diagnosis is made bylaboratory tests and a complete blood count. Treatment varies depending on the underlying cause and may include ironsupplements, blood transfusions, immunosuppressive agents, or specific drug therapies, primarily with the elimination ofthe underlying cause. Non-regenerative anemia is a very serious condition and requires timely intervention. Non-regenerative anemia in cats is an important issue in clinical practice and it is important for veterinarians to maintain theirknowledge and skills in this area.

Evaluation of Hematological, Biochemical, and Echocardiographic Findings in Dogs Infected with Dirofilaria spp.

2024-12-26T02:06:28+03:00

Canine dirofilariasis is a significant disease that associate with heart and cardiopulmonary complications. In endemic regions, the co-occurrence of other vector-borne infections further complicates diagnosis and treatment. Additionally, the lack of standardized diagnostic tools to assess disease progression represents a critical gap in veterinary literature. In this study echocardiographic, hematological, and biochemical findings of dogs infected with heartworm alone and those co-infected with other vector-borne diseases were compared. Furthermore, the study aimed to evaluate the usability of these parameters in determining the prognosis and severity of the disease. This study included 12 dogs diagnosed with Dirofilaria spp. infection, categorized into two groups: mono-infected (n=7) and co-infected (n=5). Dirofilaria antigens and additional co-infecting agents were detected using the Knott test and SNAP 4Dx, and blood samples were collected for complete blood count (CBC) and serum biochemistry analysis. Each dog underwent an echocardiographic evaluation. While most parameters were similar between the mono-infected and co-infected groups, platelet (PLT) counts and mean corpuscular hemoglobin concentration (MCHC) values were lower, and liver enzyme levels were higher in the co-infected group. Although echocardiographic parameters were generally similar, the mono-infected group showed higher left atrial dimensions and ventricular volumes, while the co-infected group exhibited slightly elevated fractional shortening (FS) and ejection fraction (EF) values. These findings suggest that co-infection may influence both platelet counts and liver enzyme levels. This study indicates that co-infections in dogs with dirofilariasis may lead to lower PLT and MCHC levels, accompanied by higher liver enzyme levels, which could impact disease management approaches.

Investigation of The Prevalence of Respiratoric Coronavirus in Dogs in Kirikkale and Surrounding Provinces

2025-01-28T17:01:35+03:00

Diseases in the lungs and other respiratory organs of dogs are usually cured with appropriate treatment. If left untreated, serious problems such as hypoxemia and sepsis occur. Canine respiratory coronavirus (CRCoV) was first identified in the United Kingdom in 2003 in a group of shelter dogs with respiratory disease. It is now detected in dogs worldwide. The disease can be found in dogs with and without clinical respiratory signs. This study aims to investigate to what extent the respiratory coronavirus is effective in the formation of respiratory complaints and to determine its prevalence in dogs. Within the scope of the thesis, 100 dogs with respiratory problems were included in the study. These were dogs brought to Kırıkkale University Veterinary Faculty Hospital, municipal shelters, and private veterinary clinics in Kırıkkale and its surroundings. Nasal and pharyngeal swab samples were analyzed using the RT-PCR technique to detect the presence of CRCoV. Analyzes showed that the incidence of CRCoV in dogs in Kırıkkale and its surroundings was 2% (2/100). This is the first study conducted in Turkey to detect the presence of canine respiratory coronavirus (CRCoV). Therefore, it will form a basis for future studies and provide an insight to the researchers.

Semi-elemental diet Gut-cumin I is capable of switching fecal scoring to fabric settings to those of acceptable levels in dogs with inflammatory bowel disease: further evidence of proof for gut-brain axis

2025-01-28T17:07:04+03:00

Polypharmacy without precise diagnosis cause harmless effects to those with gastrointestinal issues. Moreover unnecessary antibiotic usage might hasten dysbiosis, which could be detected in several dogs with gastroenteritis. Use of a novel and completely natural nutraceutical [Gut-cumin I Liquid Fomulation] against dogs with inflammatory bowel disease (ibD) whether if this natural trophic aminoacid and nutraceutical complex was capable of restoration for gastrointestinal health as detected by fecal scoring and clinical recovery/remission. A total of 59 dogs with ibD referred to the Intestinal Permeability Measurement Center (İPÖM) were entered into the study. All dogs participated, were completed the nutritional intervention protocole. Gut-cumin I was prescribed for each participant dog at a dose of 2 to 5ml/dogs based on weight of the animals for 1 week. Prior to treatment mean, median, quartile 1 (25%) and 3 (75%) fecal scoring values were deemed 2.9, 2.5, 2.0 whereas semi-elemental diet Gut-cumin I was capable of switching fecal scoring post-treatment values for mean, median, quartile 1 (25%) and 3 (75%) ranges as 3.5, 3.5, 3.,0 and 4.0, respectively. It should not be unwise to draw preliminary conclusion that semi-elemental diet Gut-cumin I was throughly altered gastrointestinal health conditions, as determined by limited access data throughly via inspeciton of fecal indices.